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Yoshihiro Uto Selected Research

Cytochalasin B

3/2006Evaluation of hypoxic cell radio-sensitizers in terms of radio-sensitizing and repair-inhibiting potential. Dependency on p53 status of tumor cells and the effects on intratumor quiescent cells.
2/2006Evaluation of hypoxia-specific cytotoxic bioreductive agent-sodium borocaptate-10B conjugates as 10B-carriers in boron neutron capture therapy.
8/2005Combination of the antivascular agent ZD6126 with hypoxic cytotoxin treatment, with reference to the effect on quiescent tumor cells and the dependency on p53 status of tumor cells.
9/2004Applicability of the 2-nitroimidazole-sodium borocaptate-10B conjugate, TX-2060, as a 10B-carrier in boron neutron capture therapy.
1/2003Usefulness of combined treatment with mild temperature hyperthermia and/or tirapazamine in the treatment of solid tumors: its independence of p53 status.
1/2003Potential of alpha-amino alcohol p-boronophenylalaninol as a boron carrier in boron neutron capture therapy, regarding its enantiomers.

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Yoshihiro Uto Research Topics

Disease

58Neoplasms (Cancer)
09/2021 - 05/2002
12Hypoxia (Hypoxemia)
01/2019 - 05/2002
6Neoplasm Metastasis (Metastasis)
01/2017 - 09/2005
5Hyperthermia
03/2014 - 01/2003
4Breast Neoplasms (Breast Cancer)
01/2017 - 07/2013
4Inflammation (Inflammations)
06/2008 - 11/2002
3Squamous Cell Carcinoma of Head and Neck
09/2021 - 11/2003
3Pancreatic Neoplasms (Pancreatic Cancer)
08/2012 - 03/2004
2Lung Neoplasms (Lung Cancer)
01/2021 - 07/2013
2Colonic Neoplasms (Colon Cancer)
01/2019 - 10/2009
2Carcinoma (Carcinomatosis)
01/2019 - 05/2002
2Pain (Aches)
01/2018 - 01/2017
2AIDS-Related Complex (ARC)
05/2017 - 03/2009
2Non-Small-Cell Lung Carcinoma (Carcinoma, Non-Small Cell Lung)
07/2016 - 11/2003
2Cardiovascular Diseases (Cardiovascular Disease)
05/2014 - 01/2013
2Prostatic Neoplasms (Prostate Cancer)
07/2013 - 03/2009
2Ascites
07/2013 - 05/2002
2Squamous Cell Carcinoma (Epidermoid Carcinoma)
12/2005 - 09/2005
1Keratitis
08/2021
1Glioma (Gliomas)
01/2021
1Neuroblastoma
01/2021
1Neutropenia
10/2020
1Bovine Mastitis
08/2020
1Ataxia Telangiectasia (Louis Bar Syndrome)
07/2019
1Sarcoma (Soft Tissue Sarcoma)
07/2019
1Cardiotoxicity
01/2019
1Hypertension (High Blood Pressure)
05/2017
1Type 2 Diabetes Mellitus (MODY)
05/2017
1Alzheimer Disease (Alzheimer's Disease)
05/2017
1Melanoma (Melanoma, Malignant)
01/2017

Drug/Important Bio-Agent (IBA)

13Proteins (Proteins, Gene)FDA Link
01/2021 - 05/2002
13vitamin D-binding protein-macrophage activating factorIBA
11/2020 - 05/2002
11Pharmaceutical PreparationsIBA
01/2021 - 05/2002
8Cytotoxins (Cytolysins)IBA
08/2012 - 05/2002
7Bromodeoxyuridine (BrdU)IBA
01/2007 - 01/2003
6Tirapazamine (SR 4233)IBA
09/2010 - 01/2003
6Cytochalasin BIBA
03/2006 - 01/2003
5protoporphyrin IXIBA
01/2021 - 08/2014
5AcidsIBA
12/2017 - 08/2014
52-nitroimidazole acetamideIBA
10/2009 - 05/2002
5SuspensionsIBA
03/2006 - 01/2003
4Phosphotransferases (Kinase)IBA
01/2021 - 03/2009
41-phenyl-3,3-dimethyltriazene (PDT)IBA
08/2018 - 07/2016
4Propolis (Bee Bread)IBA
05/2017 - 07/2007
4artepillin CIBA
05/2017 - 07/2007
4BoronIBA
08/2014 - 12/2006
43-amino-2-quinoxalinecarbonitrileIBA
12/2006 - 11/2003
3Matrix Metalloproteinases (MMPs)IBA
09/2021 - 10/2009
3Celecoxib (Celebrex)FDA Link
01/2021 - 01/2020
3EtanidazoleIBA
01/2019 - 01/2011
3DNA (Deoxyribonucleic Acid)IBA
07/2018 - 06/2005
3KetorolacIBA
01/2018 - 01/2017
3EstersIBA
05/2017 - 01/2017
3Vitamin D-Binding ProteinIBA
07/2013 - 09/2004
3TX 2100IBA
09/2010 - 02/2006
2pro-matrix metalloproteinase 9IBA
09/2021 - 09/2021
2TONS504IBA
08/2021 - 08/2018
2TAS-119IBA
01/2021 - 10/2020
2Paclitaxel (Taxol)FDA LinkGeneric
10/2020 - 01/2003
2Therapeutic UsesIBA
08/2020 - 07/2018
2EnzymesIBA
01/2019 - 03/2010
2Doxorubicin (Adriamycin)FDA LinkGeneric
01/2017 - 06/2005
2Intercellular Signaling Peptides and Proteins (Growth Factors)IBA
01/2017 - 08/2012
22- hydroxyarylidene- 4- cyclopentene- 1,3- dioneIBA
07/2016 - 03/2004
2AntioxidantsIBA
05/2014 - 05/2002
2Biological ProductsIBA
03/2014 - 09/2008
2Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA
08/2012 - 11/2003
2Indoleamine-Pyrrole 2,3,-Dioxygenase (Indoleamine 2,3 Dioxygenase)IBA
09/2010 - 09/2008
2SugarsIBA
09/2010 - 11/2006
2N-acetylcochinol-O-phosphateIBA
01/2007 - 08/2005
2Cisplatin (Platino)FDA LinkGeneric
06/2005 - 01/2003
1GelatinasesIBA
09/2021
1Transforming Growth Factors (Transforming Growth Factor)IBA
09/2021
1Matrix Metalloproteinase 14 (MT1-MMP)IBA
09/2021
1Collagenases (Collagenase)FDA Link
09/2021
1chlorinIBA
08/2021
1Cyclooxygenase 2 Inhibitors (COX-2 Inhibitors)IBA
01/2021
1valspodar (PSC 833)IBA
01/2021
1Aurora Kinase AIBA
01/2021
1Taxoids (Taxanes)IBA
10/2020
1Docetaxel (Taxotere)FDA Link
10/2020
1Drug CombinationsIBA
10/2020
1Whey ProteinsIBA
08/2020
1Protein Kinases (Protein Kinase)IBA
07/2019
1TrabectedinIBA
07/2019
1A-Form DNA (A-DNA)IBA
07/2019
1Oxidoreductases (Dehydrogenase)IBA
01/2019
1CarbonIBA
07/2018
1Schiff Bases (Schiff Base)IBA
12/2017
1caffeic acidIBA
05/2017
1ArtesunateIBA
03/2017
1Phospholipids (Phosphatides)FDA LinkGeneric
01/2017
1Ketorolac Tromethamine (Acular)FDA LinkGeneric
01/2017

Therapy/Procedure

19Therapeutics
01/2021 - 05/2002
7Immunotherapy
11/2020 - 07/2013
5Boron Neutron Capture Therapy
01/2016 - 09/2004
3Drug Therapy (Chemotherapy)
01/2021 - 03/2010
2Photochemotherapy (Photodynamic Therapy)
12/2017 - 07/2016
2Radiotherapy
01/2016 - 03/2006
1Transplantation
01/2019